Evolvability And It’s Implication In Drug Design

The ability of viral and bacterial pathogens to develop antibiotic resistance is a combination of natural selection and evolvability. The application of antibiotics to bacterial populations places them under a stressful environment. Bacteria and viruses are prokaryotes and therefore a lot of their genetic material is composed of RNA. RNA is genomically unstable and has a much higher mutation rate than DNA.

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Prions Play Protective Role In Alzheimer’s Disease

UK researchers state that prions may play a protective role in preventing the development of Alzheimer’s disease. This research states that prions help to prevent the build up of beta amyloid plaques. These are protein aggregates found in the brains of Alzheimer’s suffers, and are thought to play a role in the pathogenesis of this condition. Read the rest of this entry »

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